NEWS & PROMOTION

COVID-19

How to prevent a COVID-19?

COVID-19 is a new strain of the coronavirus in 2019, officially known as SARS-CoV-2 or COVID-19.
The first epidemic of a new strain of the corona virus in 2019 that  caused pneumonia in Wuhan, Hubei province, China. From late 2019 until present from the World Health Organization data there're about 2-4 percent death in Wuhan city. And about 0.7 percent outside Wuhan.



The incubation period and symptoms of patients:

The incubation period of this disease is generally within 14 days and most of the symptoms are between 3 to 7 days. The symptoms generally have fever, nasal congestion, sputum, cough, sneezing and pneumonia. Some people breathe quickly, panting, runny nose, diarrhea. The virus will divide and grow in human cells, such as the cells of the bronchi lining, alveoli and lung damage. Causing respiratory failure and the main cause of death The disease can cause severe disease in the elderly over 60 years and children under 7 years.
 

Distribution of infection:

China has investigated the outbreak of this outbreak in Wuhan. From the first group of people infected as workers and customers in the Huanan Seafood Wholesale Market. Aside from selling seafood Still selling meat And live animals such as ducks, chickens, donkeys, sheep, pigs, camels, foxes, snakes, badgers, rodents, hedgehogs. But at the first COVID-19 was not detected in the samples from the environment and seafood obtained from the Huanan seafood wholesale market. However, there are patients with a history of not going to this market at all.

RNA gene sequencing report (Glycoprotein spikes) of COVID-19 (MN908947) obtained from patients. The virus is found in Genus Betacoronavirus. Which is the same genus as SARS-CoV and MERS-CoV, when compared with the genetic material of the coronavirus from 271 different people and animals, found that COVID-19 is a virus caused by the mixing of genetic material between Bat's coronavirus and Cobra's coronavirus (Chinese cobra, Naja atra) allow this new species of coronavirus to spread across the species from cobra to humans. By starting with workers and customers in the market getting infected first and later the infection became more mutated. Therefore can contact from person to person.

 

Diagnosis:

Diagnosis can be done by detecting the genetic material of the infection using qRT-PCR. It can be detected in respiratory secretions.
 

Prevention of the new strain of COVID-19 Corona virus includes:

1. Avoiding traveling to Wuhan city Or the country that has an epidemic
2. If going to China Or countries that have had an outbreak in the past two weeks Then have a fever, cough,
    runny nose, sore throat, wheezing See a doctor at the hospital immediately. As well as notifying travel history as well
3. Avoid being in a crowded place In which the community should wear a mask
4. Stay away from people with respiratory symptoms such as coughing and sneezing.
5. Regularly wash hands with soap and allow water to flow for at least 20 seconds or use alcohol gel to wash hands.
6. Do not bring your hands to touch your eyes, nose or mouth unnecessarily.
7. Not sharing items with others, such as spoons, forks, chopsticks, glasses etc.

Can monitor the situation at the outbreak of new strains of the corona virus COVID-19 on the World Health Organization website 
(https://www.who.int/emergencies/diseases/novel-coronavirus-2019)

More information about the new strain of the Corona virus 2019​!

In the beginning, it was thought that it was an infection from animals to humans. When there was news of this outbreak the world is closely watching. Because it is experienced from serious respiratory illnesses caused by the corona virus, such as Severe Acute Respiratory Syndrome (SARS) that occurred during 2002-2003 caused by the corona virus the SARS-CoV strain, a corona virus, crosses species from bats through musk. To become infected in humans by starting to spread from China and spread all over the world with over eight thousand people infected. The death rate is about 10 percent and increases to 50 percent in the elderly.

In 2012-2014 there is an epidemic of Middle East respiratory syndrome coronavirus (MERS-CoV) which crosses the species from bats through camels. Human infection begin with patients in Saudi Arabia a total of 1,733 peoples were infected. The approximately of death is 36 percent.

The corona virus is the largest virus with the genetic material RNA. And there is an outer covering consisting of proteins covered with spikes of carbohydrates protruding from virus particles when viewed with an electron microscope will be seen as a crown (Latin corona, meaning crown or crown) surrounded, therefore, is the origin of the name of the virus in this group that has many members. Infected with disease in both people and many animals such as poultry, mammals (horses, cows, cats, dogs, bats, rabbits, rats, camels and other wildlife) and reptiles such as snakes. Therefore, the corona virus species that cause diseases in both the respiratory system and digestive tract may spread to humans and cause disease in humans (zoonotic infection).

The corona virus is divided into 4 genus, Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. The disease-causing corona virus in humans that causes mild respiratory symptoms and often have no symptoms as classified in Genus Alphacoronavirus. Coronal viruses that cause severe disease in humans and cross species from animals such as SARS-CoV and MERS-CoV are in Genus Betacoronavirus.

The corona virus has a genetic material that is RNA, therefore it has a high chance of mutation and can cause more cross-infection. In places that gather these animals massively, as in the animal market for food That is the source of SARS-CoV transmission from musk to humans.

The epidemic situation of the new strain of COVID-19 from China. From the first reported on December 31, 2019, was found in patients with unknown pneumonia in Wuhan continue increased. It was officially reported on 3 January 2020 that pneumonia at Wuhan caused by a new strain of the corona virus 2019 and can spread from person to person.

Reported to 24 January 2020. In China there are 571 peoples infected the new strains of the corona virus, which have died 18 peoples, 17 are in Wuhan and 1 have died outside of Wuhan in Hebei. Most of the deceased are elderly.

There are 10 cases of COVID-19 infection outside of China, from Thailand, Japan, South Korea, Taiwan, Hong Kong, Macau, and most recently from the United States. All have travel history from Wuhan city. In China, COVID-19 has been reported in other cities besides Wuhan, such as Guangdong, Beijing, Shanghai etc. The number of people infected is likely to increase.

According to a World Health Organization meeting on 23 January 2020, the global health emergencies are not yet announced, with special precautions in the outbreak of China. Which China has announced lockdown of Wuhan city, controlling travel from this city and extended to close the city of Huanggang, adjacent to Wuhan, about 30 miles east, and there will be no Chinese New Year celebrations in public in Beijing.

Supporting information 24 Jan 63 Compilation documents :
  1. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 cited on 23 January 2020.
  2. https://www.cdc.gov/coronavirus/2019-ncov cited on 23 January 2020.
  3. Ji W, Wang W, Zhao X, Zai J, Li X. Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross-species transmission from snake to human. J Med Virol 2020; https://doi.org/10.1002/jmv.25682.
  4. tmc.or.th